Stem cells used to treat or cure the disease or condition is known as stem cell therapy  Currently mostly used therapy is bone marrow transplant and some are derived from umbilical cord also in wide use  Stem cells identified by functional essays and the markers are genes and their products are isolated to identify the stem cells  Embryonic stem cells (ESCs) were classified and isolated by using Molecular biomarkers and monitor their differentiation by antibody based techniques  Several people suffering from common diseases like neurodegenerative diseases, dementia, arthritis, diabetes, cardiac infarction, stroke and the lifelong therapy leads to huge cost in healthcare system where stem cell therapy offers a great potential for the treatment of these type of diseases